Article
Frequent occurrence of uniparental disomy in colorectal cancer.
Carcinogenesis - 1 Jan 2007
Andersen Claus Lindbjerg, Wiuf Carsten, Kruhøffer Mogens, Korsgaard Marianne, Laurberg Søren, Ørntoft Torben Falck
Abstract excerpt
We used SNP arrays to identify and characterize genomic alterations associated with colorectal cancer (CRC). Laser microdissected cancer cells from 15 adenocarinomas were investigated by Affymetrix Mapping 10K SNP arrays. Analysis of the data extracted from the SNP arrays revealed multiple regions with copy number alterations and loss of heterozygosity (LOH). Novel LOH areas were identified at chromosomes 13, 14...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
