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Article

The downstream modulator of interferon-gamma, STAT1 is not genetically associated to the Dutch coeliac disease population.

European journal of human genetics : EJHG - 1 Oct 2006

Diosdado Begoña, Monsuur Alienke J, Mearin María Luisa, Mulder Chris, Wijmenga Cisca

Abstract excerpt

Coeliac disease (CD) is a complex genetic disorder. Its etiology is owing to multiple genes and environmental factors, such as gluten. The first event in the pathogenesis of CD after the ingestion of gluten is the activation of a Th1 immune response that leads to villous atrophy. Although this immune response seems crucial to the disease's development, only the HLA-DQ2/DQ8 genes have been identified as causative...

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Source

Identifiers

PMID: 16773129
DOI: 10.1038/sj.ejhg.5201667

Genes

STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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