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Article

The interferon gamma gene in celiac disease: augmented expression correlates with tissue damage but no evidence for genetic susceptibility.

Journal of autoimmunity - 1 Sept 2004

Wapenaar Martin C, van Belzen Martine J, Fransen Justin H, Sarasqueta Aranzazu Fariña, Houwen Roderick H J, Meijer Jos W R, Mulder Chris J J, Wijmenga Cisca

Abstract excerpt

Celiac disease (CD) is a complex genetic disorder characterized by gluten intolerance. The Th1 immune response, with a key position for interferon gamma (IFN-gamma), is an important determinant of intestinal remodeling in CD. We aimed at further ascertaining the role of IFN-gamma, either as a gen...

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Source

Identifiers

PMID: 15324937
DOI: 10.1016/j.jaut.2004.05.004

Genes

IFNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15324937-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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