Article
APOE-[epsilon]2 allele associated with higher prevalence of sporadic Parkinson disease.
Neurology - 22 Jun 2004
Huang Xuemei, Chen Peter C, Poole Charles
Abstract excerpt
BACKGROUND: The link of the apolipoprotein (APOE) -epsilon4 allele to Alzheimer disease (AD) has led to studies investigating the role of apoE polymorphisms in Parkinson disease (PD). The authors hypothesized that any association between PD and APOE alleles and genotypes would be too small to be detected or precisely estimated by an individual case-controlled study. METHOD: The hypothesis was tested by systematic...
Topics
- Alleles
- Apolipoprotein E2
- Apolipoproteins E
- Gene Frequency
- Genotype
- Humans
- Parkinson Disease
- Polymorphism, Genetic
- Prevalence