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Article

Histone H2B.8 compacts flowering plant sperm through chromatin phase separation.

Nature - 1 Nov 2022

Buttress Toby, He Shengbo, Wang Liang, Zhou Shaoli, Saalbach Gerhard, Vickers Martin, Li Guohong, Li Pilong, Feng Xiaoqi

Abstract excerpt

Sperm chromatin is typically transformed by protamines into a compact and transcriptionally inactive state1,2. Sperm cells of flowering plants lack protamines, yet they have small, transcriptionally active nuclei with chromatin condensed through an unknown mechanism3,4. Here we show that a histone variant, H2B.8, mediates sperm chromatin and nuclear condensation in Arabidopsis thaliana. Loss of H2B.8 causes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36323776
DOI: 10.1038/s41586-022-05386-6
PMCID: PMC9668745

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