Article
Peroxisome proliferator-activated receptor-gamma polymorphism, body mass and prostate cancer risk: evidence for gene-environment interaction.
Oncology - 1 Jan 2006
Zmuda Joseph M, Modugno Francesmary, Weissfeld Joel L, Cauley Jane A, Trump Donald L, Moffett Susan P, Ferrell Robert E
Abstract excerpt
BACKGROUND: Peroxisome proliferator-activated receptor (PPAR)-gamma has been implicated in prostate cancer. In the present case-control study, we tested if a common Pro12Ala polymorphism in PPAR-gamma is associated with the risk of prostate cancer. METHODS: Ninety-one adult Caucasians with prostate cancer were recruited between 1994 and 1998. Blood samples were also obtained from 237 community-based Caucasian men...
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