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Article

Interaction between a peroxisome proliferator-activated receptor gamma gene polymorphism and dietary fat intake in relation to body mass.

Human molecular genetics - 15 Nov 2003

Memisoglu Asli, Hu Frank B, Hankinson Susan E, Manson JoAnn E, De Vivo Immaculata, Willett Walter C, Hunter David J

Abstract excerpt

The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a critical regulator of adipogenesis. PPAR gamma+/- mice are resistant to high-fat diet-induced obesity and thus PPAR gamma may mediate physiological responses to dietary fat in other mammals. The aim of this study was to determine whether the human PPAR gamma proline to alanine substitution polymorphism (Pro12Ala) modifies the association...

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Identifiers

PMID: 14506127
DOI: 10.1093/hmg/ddg318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction between a peroxisome proliferator-activated receptor gamma gene polymorphism and dietary fat intake in relation to body mass.PMID 14506127Read ↗

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Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis.Semantic proximity Read ↗

The Pro12Ala PPARgamma2 variant determines metabolism at the gene-environment interface.Semantic proximity Read ↗

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PPARγ2 gene Pro12Ala and PPARα gene Leu162Val single nucleotide polymorphisms interact with dietary intake of fat in determination of plasma lipid concentrations.Semantic proximity Read ↗

The Peroxisome Proliferator-Activated Receptor-γ2 Pro12Ala PolymorphismSemantic proximity Read ↗

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