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Article

Interactions of peroxisome proliferator-activated receptor {gamma} and diet in etiology of colorectal cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2005

Murtaugh Maureen A, Ma Khe-Ni, Caan Bette J, Sweeney Carol, Wolff Roger, Samowitz Wade S, Potter John D, Slattery Martha L

Abstract excerpt

The peroxisome proliferator-activated receptor gamma (PPARgamma) is one of a group of ligand-activated nuclear receptors responsible for regulation of glucose, lipid homeostasis, cell differentiation, and apoptosis. The 12 proline-to-alanine (Pro12Ala) substitution polymorphism in PPARgamma produces proteins with lower activity. Variation in PPARgamma expression in the bowel and the role of dietary fatty acids as...

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Identifiers

PMID: 15894676
DOI: 10.1158/1055-9965.EPI-04-0681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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