Article
Possible association of norepinephrine transporter -3081(A/T) polymorphism with methylphenidate response in attention deficit hyperactivity disorder.
Behavioral and brain functions : BBF - 7 Oct 2010
Kim Boong-Nyun, Kim Jae-Won, Hong Soon Beom, Cho Soo-Churl, Shin Min-Sup, Yoo Hee-Jeong
Abstract excerpt
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a heritable disorder characterized by symptoms of inattention and/or hyperactivity/impulsivity. Methylphenidate (MPH) has been shown to block the norepinephrine transporter (NET), and genetic investigations have demonstrated that the norepinephrine transporter gene (SLC6A2) is associated with ADHD. The aims of this study were to examine the...
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