Article
A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus.
The FEBS journal - 1 Jul 2006
Reeves Emer P, Reiber Kathrin, Neville Claire, Scheibner Olaf, Kavanagh Kevin, Doyle Sean
Abstract excerpt
Aspergillus fumigatus is an important human fungal pathogen. The Aspergillus fumigatus genome contains 14 nonribosomal peptide synthetase genes, potentially responsible for generating metabolites that contribute to organismal virulence. Differential expression of the nonribosomal peptide synthetase gene, pes1, in four strains of Aspergillus fumigatus was observed. The pattern of pes1 expression differed from that...
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