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Article

Targeted disruption of nonribosomal peptide synthetase pes3 augments the virulence of Aspergillus fumigatus.

Infection and immunity - 1 Oct 2011

O'Hanlon Karen A, Cairns Timothy, Stack Deirdre, Schrettl Markus, Bignell Elaine M, Kavanagh Kevin, Miggin Sinéad M, O'Keeffe Grainne, Larsen Thomas O, Doyle Sean

Abstract excerpt

Nonribosomal peptide synthesis (NRPS) is a documented virulence factor for the opportunistic pathogen Aspergillus fumigatus and other fungi. Secreted or intracellularly located NRP products include the toxic molecule gliotoxin and the iron-chelating siderophores triacetylfusarinine C and ferricro...

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Identifiers

PMID: 21746855
DOI: 10.1128/IAI.00192-11
PMCID: PMC3187245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-21746855-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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Targeted disruption of nonribosomal peptide synthetase pes3 augments the virulence of Aspergillus fumigatus.PMID 21746855Read ↗

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