Article
Use of a penetratin-linked peptide in Dictyostelium.
Molecular biotechnology - 1 Jun 2006
Ryves W Jonathan, Harwood Adrian J
Abstract excerpt
The plasma membrane is an effective barrier to most macromolecules and hydrophilic molecules. Remarkably, a class of positively charged cell-penetrating peptides (CPPs) has been discovered that can translocate themselves and associated cargoes into the cytoplasm. These have been used to carry oligopeptide- and oligonucleotide-based inhibitors into mammalian cells. A recent report indicates that the same CPPs are...
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