Article
Cell-cell contact mediates cAMP secretion in Dictyostelium discoideum.
Developmental genetics - 1 Jan 1991
Fontana D R, Price P L, Phillips J C
Abstract excerpt
Cyclic adenosine 3':5' monophosphate (cAMP) and cell-cell contact regulate developmental gene expression in Dictyostelium discoideum. Developing D. discoideum amoebae synthesize and secrete cAMP following the binding of cAMP to their surface cAMP receptor, a response called cAMP signaling. We have demonstrated two responses of developing D. discoideum amoebae to cell-cell contact. Cell-cell contact elicits cAMP...
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