Article
Synthesis and studies on cell-penetrating peptides.
Bioconjugate chemistry - 1 Jul 2009
Bertrand Jean-Remi, Malvy Claude, Auguste Tiphanie, Tóth Gábor K, Kiss-Ivánkovits Orsolya, Illyés Eszter, Hollósi Miklós, Bottka Sándor, Laczkó Ilona
Abstract excerpt
The ability of different synthetic cell penetrating peptides, as Antennapedia (wild and Phe(6) mutated penetratins), flock house virus, and integrin peptides to form complexes with a 25mer antisense oligonucleotide was compared and their conformation was determined by circular dichroism spectroscopy. The efficiency for oligonucleotide delivery into cells was measured using peptides labeled with a coumarin...
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