Article
Multiple testing in candidate gene situations: a comparison of classical, discrete, and resampling-based procedures.
Statistical applications in genetics and molecular biology - 1 Jan 2011
Elsäβer Amelie, Victor Anja, Hommel Gerhard
Abstract excerpt
In candidate gene association studies, usually several elementary hypotheses are tested simultaneously using one particular set of data. The data normally consist of partly correlated SNP information. Every SNP can be tested for association with the disease, e.g., using the Cochran-Armitage test for trend. To account for the multiplicity of the test situation, different types of multiple testing procedures have...
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