Article
Influence of eNOS gene polymorphisms (894G/T; - 786C/T) on postoperative hemodynamics after cardiac surgery.
The Thoracic and cardiovascular surgeon - 1 Jun 2006
Liakopoulos O J, Dörge H, Popov A F, Schmitto J D, Cattaruzza M, Schoendube F A
Abstract excerpt
BACKGROUND: Differences in vascular reactivity have been associated with variable NO release due to 894G/T and -786C/T polymorphisms of the eNOS gene. Carriers of the 894T and -786C alleles are known to have enhanced vascular responsiveness to vasoconstrictor stimulation due to decreased NO generation. Thus, we hypothesized that eNOS gene polymorphism could influence perioperative hemodynamics and catecholamine...
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