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Article

Effects of β-Adrenoceptor and Catechol-O-Methyl-Transferase (COMT) Polymorphism on Postoperative Outcome in Cardiac Surgery Patients.

Medical science monitor basic research - 19 May 2017

Dhein Stefan, Dohmen Pascal M, Sauer Matthias, Tews Julia, Weickmann Johannes, Funkat Anne-Kathrin, Misfeld Martin, Borger Michael A, Mohr Friedrich W

Abstract excerpt

BACKGROUND There is a long-standing debate about the role of beta-adrenoceptor polymorphisms in the cardiovascular system. We wanted to elucidate whether β1-adrenoceptor-polymorphisms affects the postoperative catecholamine consumption and the length of intermediate care unit stay in patients undergoing cardiac surgery, and whether this might be enhanced or attenuated by catechol-O-methyl-transferase (COMT)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28522796
DOI: 10.12659/msmbr.902820
PMCID: PMC5445899

Genes

COMT

Provenance

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Effects of β-Adrenoceptor and Catechol-O-Methyl-Transferase (COMT) Polymorphism on Postoperative Outcome in Cardiac Surgery Patients.PMID 28522796Read ↗

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OPRM1 and COMT polymorphisms: implications on postoperative acute, chronic and experimental pain after cardiac surgery.Semantic proximity Read ↗

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