Article
The C523A beta2 adrenergic receptor polymorphism associates with markers of asthma severity in African Americans.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Apr 2006
Lima John J, Holbrook Janet T, Wang Jianwei, Sylvester James E, Blake Kathryn V, Blumenthal Malcolm N, Castro Mario, Hanania Nicholas, Wise Robert
Abstract excerpt
Our goal was to explore associations between ss2 adrenergic receptor polymorphisms and markers of asthma severity in African American and Caucasian patients with asthma. Polymorphisms at loci -1023, -654, -47, 46, 79, 491, and 523 were genotyped and haplotypes were imputed in 143 African Americans and 336 Caucasians. C523A genotype associated with percentage of African Americans (but not of Caucasians) having an...
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