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Article

Methods to rapidly and accurately screen a large number of ENU mutagenized mice for abnormal motor phenotypes.

Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases - 1 Jun 2006

Abramow-Newerly Wanda, Lipina Tatiana, Abramow-Newerly Maria, Kim Daniel, Bechard Allison R, Xie Gang, Clapcote Steve J, Roder John C

Abstract excerpt

In a dominant genetic screen for late-onset motor impairments in mice, 16-20-week-old N-nitroso-N-ethylurea (ENU)-mutagenized females were subjected to a behavioural test battery consisting of a visual assessment followed by the vertical pole, rotarod and grip strength tests. SOD1-G93A transgenic mice were tested in parallel as a positive control to provide information on the validity and sensitivity of the...

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PMID: 16753976
DOI: 10.1080/14660820500443000

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SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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