Article
Implementation of the modified-SHIRPA protocol for screening of dominant phenotypes in a large-scale ENU mutagenesis program.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 2005
Masuya Hiroshi, Inoue Maki, Wada Yumiko, Shimizu Aya, Nagano Junko, Kawai Akiko, Inoue Ayako, Kagami Tomoko, Hirayama Taeko, Yamaga Ayako, Kaneda Hideki, Kobayashi Kimio, Minowa Osamu, Miura Ikuo, Gondo Yoichi, Noda Tetsuo, Wakana Shigeharu, Shiroishi Toshihiko
Abstract excerpt
SHIRPA is a three-stage protocol for the comprehensive assessment of primarily mouse behavior. The first stage consists of high-throughput phenotyping of 33 behavioral observations and 7 metabolic or disease observations. We modified this part of the protocol by integrating new morphologic observations into the initial phenotype assay of behavior and dysmorphology. Behavioral observations assessed by this...
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