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Article

Fatty acid auxotrophy in Drosophila larvae lacking SREBP.

Cell metabolism - 1 Jun 2006

Kunte Amit S, Matthews Krista A, Rawson Robert B

Abstract excerpt

SREBPs are membrane bound transcription factors that are crucial for normal lipid synthesis in animal cells. Here, we show that Drosophila lacking dSREBP die before the third larval instar. Mutant larvae exhibit pronounced growth defects prior to lethality, along with substantial deficits in the...

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PMID: 16753579
DOI: 10.1016/j.cmet.2006.04.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16753579-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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