Article
Creutzfeldt-Jakob disease in United Kingdom patients treated with human pituitary growth hormone.
Neurology - 23 Sept 2003
Swerdlow A J, Higgins C D, Adlard P, Jones M E, Preece M A
Abstract excerpt
OBJECTIVE: To investigate risk factors for Creutzfeldt-Jakob disease (CJD) in patients in the United Kingdom treated with human pituitary growth hormone (hGH). METHODS: Incidence rates of CJD, based on person-year denominators, were assessed in a cohort of 1,848 patients treated with hGH in the United Kingdom from 1959 through 1985 and followed to the end of 2000. RESULTS: CJD developed in 38 patients. Risk of...
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