Article
Variation in MLH1 distribution in recombination maps for individual chromosomes from human males.
Human molecular genetics - 1 Aug 2006
Sun Fei, Oliver-Bonet Maria, Liehr Thomas, Starke Heike, Turek Paul, Ko Evelyn, Rademaker Alfred, Martin Renée H
Abstract excerpt
Meiotic recombination is essential for the segregation of homologous chromosomes and the formation of normal haploid gametes. Little is known about patterns of meiotic recombination in human germ cells or the mechanisms that control these patterns. Documentation of the normal range of variability of recombination distribution over the genome among individuals is an essential prerequisite for understanding...
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