Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of the pfl gene and resulting metabolite flux distribution in nuo and ackA-pta E. coli mutant strains.

Biotechnology progress - 1 Jan 2000

Singh Randeep, Yang Yea-Tyng, Lu Biqing, Bennett George N, San Ka-Yiu

Abstract excerpt

Our laboratory previously studied the interaction between nuo and the acetate-producing pathway encoded by ackA-pta in Escherichia coli. We examined metabolic patterns, particularly the ethanol and acetate production rates, of several mutant strains grown under anaerobic growth conditions. Since the pyruvate formate-lyase (PFL) pathway is the major route for acetyl-CoA and formate production under anaerobic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetates
Share to Acetyltransferases
Share to Anaerobiosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ethanol

Share to Gene Expression Regulation, Bacterial

Share to Gene Expression Regulation, Enzymologic

Share to Multigene Family

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 16739977
DOI: 10.1021/bp050326h

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of the pfl gene and resulting metabolite flux distribution in nuo and ackA-pta E. coli mutant strains.PMID 16739977Read ↗

Effect of inactivation of nuo and ackA-pta on redistribution of metabolic fluxes in Escherichia coli.Semantic proximity Read ↗

Characterization of the acetate-producing pathways in Escherichia coli.Semantic proximity Read ↗

Redistribution of metabolic fluxes in the central aerobic metabolic pathway of E. coli mutant strains with deletion of the ackA-pta and poxB pathways for the synthesis of isoamyl acetate.Semantic proximity Read ↗

Enhancement of lactate and succinate formation in adhE or pta-ackA mutants of NADH dehydrogenase-deficient Escherichia coli.Semantic proximity Read ↗

Comparison of different strategies to reduce acetate formation in Escherichia coli.Semantic proximity Read ↗

Production of isoamyl acetate in ackA-pta and/or ldh mutants of Escherichia coli with overexpression of yeast ATF2.Semantic proximity Read ↗

Pyruvate Production by Escherichia coli by Use of Pyruvate Dehydrogenase Variants.Semantic proximity Read ↗

Metabolic flux analysis of Escherichia coli deficient in the acetate production pathway and expressing the Bacillus subtilis acetolactate synthase.Semantic proximity Read ↗

Consequences of phosphoenolpyruvate:sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution in Escherichia coli.Semantic proximity Read ↗

Construction of Pta-Ack pathway deletion mutants of Escherichia coli and characteristic growth profiles of the mutants in a rich medium.Semantic proximity Read ↗

An insight into the role of phosphotransacetylase (pta) and the acetate/acetyl-CoA node in Escherichia coli.Semantic proximity Read ↗

The effect of acetate pathway mutations on the production of pyruvate in Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.