Article
Deletion of the rpoZ gene, encoding the omega subunit of RNA polymerase, results in pleiotropic surface-related phenotypes in Mycobacterium smegmatis.
Microbiology (Reading, England) - 1 Jun 2006
Mathew Renjith, Mukherjee Raju, Balachandar Radhakrishnan, Chatterji Dipankar
Abstract excerpt
The omega subunit, the smallest subunit of bacterial RNA polymerase, is known to be involved in maintaining the conformation of the beta' subunit and aiding its recruitment to the rest of the core enzyme assembly in Escherichia coli. It has recently been shown in Mycobacterium smegmatis, by creating a deletion mutation of the rpoZ gene encoding omega, that the physiological role of the omega subunit also includes...
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