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Article

Regulation of cell proliferation by the antizyme inhibitor: evidence for an antizyme-independent mechanism.

Journal of cell science - 15 Jun 2006

Kim Sonia W, Mangold Ursula, Waghorne Carol, Mobascher Arian, Shantz Lisa, Banyard Jacqueline, Zetter Bruce R

Abstract excerpt

The antizyme inhibitor was discovered as a protein that binds to the regulatory protein antizyme and inhibits the ability of antizyme to interact with the enzyme ornithine decarboxylase (ODC). Blocking antizyme activity subsequently leads to increased intracellular levels of ODC and increased ODC enzymatic activity. We now report that antizyme inhibitor is a positive modulator of cell growth. Overexpression of...

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Identifiers

PMID: 16735445
DOI: 10.1242/jcs.02966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulation of cell proliferation by the antizyme inhibitor: evidence for an antizyme-independent mechanism.PMID 16735445Read ↗

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