Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of ornithine decarboxylase antizyme inhibitor in vivo.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Jan 2009

Tang Hua, Ariki Kimi, Ohkido Makiko, Murakami Yasuko, Matsufuji Senya, Li Zhenghua, Yamamura Ken-ichi

Abstract excerpt

Ornithine decarboxylase (ODC) antizyme inhibitor (AZI) has been shown to regulate ODC activity in cell cultures. However, its biological functions in an organism remain unknown. An embryonic stem (ES) cell clone was established, in which the Azin1 gene was disrupted by the gene trap technique. To identify the function of Azin1 gene in vivo, a mutant mouse line was generated using these trapped ES cells....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to Cell Line
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Vectors

Share to Heterozygote

Share to Homozygote

Share to Mice, Mutant Strains

Share to Polyamines

Source

Identifiers

PMID: 19077035
DOI: 10.1111/j.1365-2443.2008.01249.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of ornithine decarboxylase antizyme inhibitor in vivo.PMID 19077035Read ↗

Regulation of cell proliferation by the antizyme inhibitor: evidence for an antizyme-independent mechanism.Semantic proximity Read ↗

New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motilitySemantic proximity Read ↗

Polyamine biosynthesis in <i>Xenopus laevis:</i> the gene xlAZIN2/xlODC2 encodes a lysine decarboxylaseSemantic proximity Read ↗

Regulation of ornithine decarboxylase.Semantic proximity Read ↗

Mga is essential for the survival of pluripotent cells during peri-implantation development.Semantic proximity Read ↗

OAZ-t/OAZ3 Is Essential for Rigid Connection of Sperm Tails to Heads in MouseSemantic proximity Read ↗

Putrescine independent wound response phenotype is produced by ODC-like RNAi in planarians.Semantic proximity Read ↗

Antizyme inhibitor 2 (AZIN2/ODCp) stimulates polyamine uptake in mammalian cells.Semantic proximity Read ↗

Critical factors governing the difference in antizyme-binding affinities between human ornithine decarboxylase and antizyme inhibitor.Semantic proximity Read ↗

Transgenic animals modelling polyamine metabolism-related diseases.Semantic proximity Read ↗

Targeted killing of a mammalian cell based upon its specialized metabolic stateSemantic proximity Read ↗

Induction of epithelial differentiation and DNA demethylation in hamster malignant oral keratinocyte by ornithine decarboxylase antizyme.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.