Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional silencing of an amoebapore gene in Entamoeba histolytica: molecular analysis and effect on pathogenicity.

Eukaryotic cell - 1 Apr 2003

Bracha Rivka, Nuchamowitz Yael, Mirelman David

Abstract excerpt

Transcriptional silencing of the gene coding for amoebapore A (AP-A) was observed when trophozoites of Entamoeba histolytica were transfected with a hybrid plasmid construct containing the ap-a gene flanked by the upstream and downstream segments of the original Ehap-a gene. Transfectants were totally devoid of ap-a transcript and AP-A protein. An identical silencing effect was observed upon transfection with a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Flanking Region
Share to 5' Flanking Region
Share to Clone Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Entamoeba histolytica

Share to Ion Channels

Share to Protozoan Proteins

Share to RNA, Double-Stranded

Share to Silencer Elements, Transcriptional

Source

Open in PubMed Open full text

Identifiers

PMID: 12684379
DOI: 10.1128/EC.2.2.295-305.2003
PMCID: PMC154849

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional silencing of an amoebapore gene in Entamoeba histolytica: molecular analysis and effect on pathogenicity.PMID 12684379Read ↗

Transcriptional Silencing of Multiple Genes in Trophozoites of Entamoeba histolyticaSemantic proximity Read ↗

Antisense inhibition of amoebapore expression in<i>Entamoeba histolytica</i>causes a decrease in amoebic virulenceSemantic proximity Read ↗

Major cysteine peptidases of <i>Entamoeba histolytica</i> are required for aggregation and digestion of erythrocytes but are dispensable for phagocytosis and cytopathogenicitySemantic proximity Read ↗

Nucleus-localized Antisense Small RNAs with 5′-Polyphosphate Termini Regulate Long Term Transcriptional Gene Silencing in Entamoeba histolytica G3 StrainSemantic proximity Read ↗

Transfection and continuous expression of heterologous genes in the protozoan parasite Entamoeba histolytica.Semantic proximity Read ↗

Proteins differentially expressed between pathogenic and non-pathogenic <i>Entamoeba histolytica</i> clones influence pathogenicity by different mechanismsSemantic proximity Read ↗

Robust gene silencing mediated by antisense small RNAs in the pathogenic protist Entamoeba histolyticaSemantic proximity Read ↗

Transcriptional gene silencing reveals two distinct groups of Entamoeba histolytica Gal/GalNAc-lectin light subunits.Semantic proximity Read ↗

Genes differentially expressed between pathogenic and non-pathogenic Entamoeba histolytica clones influence pathogenicity-associated phenotypes by multiple mechanisms.Semantic proximity Read ↗

Development of Approaches for Transgene Expression in the Pathogenic Free-Living Amoeba <em>Naegleria fowleri</em>Semantic proximity Read ↗

Overexpression of Specific Cysteine Peptidases Confers Pathogenicity to a Nonpathogenic Entamoeba histolytica CloneSemantic proximity Read ↗

Use of bacterially expressed dsRNA to downregulate Entamoeba histolytica gene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.