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Article

Molecular approaches to developmental malformations using analogous forms of valproic acid.

Congenital anomalies - 1 Jun 2006

Okada Akinobu, Fujiwara Michio

Abstract excerpt

The teratogenic potential of valproic acid has been well established both in experimental models and in human clinical studies. Evidence from many previous studies has shown that VPA is an appropriate drug model for studying chemical structure-teratogenicity relationships. Using molecular techniques of DNA microarray (GeneChip system) or quantitative real-time polymerase chain reaction with low teratogenic VPA...

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Identifiers

PMID: 16732764
DOI: 10.1111/j.1741-4520.2006.00105.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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