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Article

Valproic acid-induced skeletal malformations: associated gene expression cascades.

Pharmacogenetics and genomics - 1 Nov 2005

Massa Valentina, Cabrera Robert M, Menegola Elena, Giavini Erminio, Finnell Richard H

Abstract excerpt

OBJECTIVES: Valproic acid (VPA) is a widely used anticonvulsant medication with well-known teratogenic effects in both humans and in experimental animal model systems. The most commonly observed malformations induced by VPA in experimental animals include neural and skeletal defects. In this stud...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16220111
DOI: 10.1097/01.fpc.0000170914.11898.3a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16220111-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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