Article

Valproic acid embryopathy: Report of two siblings with further expansion of the phenotypic abnormalities and a review of the literature

2001-01-15

Abstract excerpt

Fetal Valproate Syndrome (FVS) results from prenatal exposure to valproic acid (VPA). It is characterized by a distinctive facial appearance, a cluster of minor and major anomalies, and central nervous system dysfunction. In this study, two siblings who were exposed to monotherapy with VPA are described with documentation of long-term follow up. Both children had craniofacial findings, multiple systemic and orthop...

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Literature Corpus work: fc62d0f0-64ed-5e4e-b2b4-519a6175d95f
DOI: 10.1002/1096-8628(20010115)98:2<168::aid-ajmg1026>3.3.co;2-f

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