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Article

Understanding the overdispersed molecular clock.

Genetics - 1 Mar 2000

Cutler D J

Abstract excerpt

Rates of molecular evolution at some protein-encoding loci are more irregular than expected under a simple neutral model of molecular evolution. This pattern of excessive irregularity in protein substitutions is often called the "overdispersed molecular clock" and is characterized by an index of dispersion, R(T) > 1. Assuming infinite sites, no recombination model of the gene R(T) is given for a general...

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Identifiers

PMID: 10757779
DOI: 10.1093/genetics/154.3.1403
PMCID: PMC1461005

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