Article
The modern molecular clock.
Nature reviews. Genetics - 1 Mar 2003
Bromham Lindell, Penny David
Abstract excerpt
The discovery of the molecular clock--a relatively constant rate of molecular evolution--provided an insight into the mechanisms of molecular evolution, and created one of the most useful new tools in biology. The unexpected constancy of rate was explained by assuming that most changes to genes are effectively neutral. Theory predicts several sources of variation in the rate of molecular evolution. However, even...
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