Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2.

doi:10.1086/377139

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Article

Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2.

American journal of human genetics - 1 Aug 2003

Reynisdottir Inga, Thorleifsson Gudmar, Benediktsson Rafn, Sigurdsson Gunnar, Emilsson Valur, Einarsdottir Anna Sigurlin, Hjorleifsdottir Eyrun Edda, Orlygsdottir Gudbjorg Th, Bjornsdottir Gudrun Thora, Saemundsdottir Jona, Halldorsson Skarphedinn, Hrafnkelsdottir Soffia, Sigurjonsdottir Steinunn Bjorg, Steinsdottir Svana, Martin Mitchell, Kochan Jarema P, Rhees Brian K, Grant Struan F A, Frigge Michael L, Kong Augustine, Gudnason Vilmundur, Stefansson Kari, Gulcher Jeffrey R

Abstract excerpt

We report a genomewide linkage study of type 2 diabetes (T2D [MIM 125853]) in the Icelandic population. A list of type 2 diabetics was cross-matched with a computerized genealogical database clustering 763 type 2 diabetics into 227 families. The diabetic patients and their relatives were genotyped with 906 microsatellite markers. A nonparametric multipoint linkage analysis yielded linkage to 5q34-q35.2 (LOD =...

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PMID: 12851856
DOI: 10.1086/377139
PMCID: PMC1180371

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