Article
An update on molecular genetics of gastrointestinal stromal tumours.
Journal of clinical pathology - 1 Jun 2006
Tornillo L, Terracciano L M
Abstract excerpt
Gastrointestinal stromal tumours (GISTs) are the most common primary mesenchymal tumours of the gastrointestinal tract. Most of them show activating mutations of the genes coding for KIT or platelet-derived growth factor receptor alpha (PDGFRalpha), two receptor tyrosine kinases (RTKs). The RTK i...
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