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Article

GPR54 and kisspeptin in reproduction.

Human reproduction update - 1 Jan 2000

Tena-Sempere Manuel

Abstract excerpt

Kisspeptins, the peptide products of the KiSS-1 gene, were identified in 2001 as natural ligands of the previously orphan G protein-coupled receptor, GPR54. They include, among others, metastin and kisspeptin-10. The known biological functions of kisspeptins were initially restricted to their ability to suppress tumour metastasis, hence the name of metastin. However, in late 2003, two groups independently...

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Identifiers

PMID: 16731583
DOI: 10.1093/humupd/dml023

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