Cross talk between germ cells and gonadal somatic cells is critical for sex differentiation of the gonads in the teleost fish, medaka (Oryzias latipes)

Abstract excerpt

To evaluate the possible role of germ cells on sex differentiation of the gonads in vertebrates, the teleost fish, medaka (Oryzias latipes), was used to generate a gonad without germ cells. The germ cell-deficient medaka reveals multiple effects of germ cells on the process of sex differentiation. The previously isolated mutant medaka, hotei, with the excessive number of germ cells may support the contention that...

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