Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1 Subtype C Drug Resistance Mutations in Heavily Treated Patients Failing Integrase Strand Transfer Inhibitor-Based Regimens in Botswana.

Viruses - 31 Mar 2021

Seatla Kaelo K, Maruapula Dorcas, Choga Wonderful T, Ntsipe Tshenolo, Mathiba Nametso, Mogwele Mompati, Kapanda Max, Nkomo Bornapate, Ramaabya Dinah, Makhema Joseph, Mmalane Mompati, Mine Madisa, Kasvosve Ishmael, Lockman Shahin, Moyo Sikhulile, Gaseitsiwe Simani

Abstract excerpt

There are limited real-world mutational and virological outcomes data of treatment-experienced persons diagnosed with HIV-1 subtype C (HIV-1 C) who are failing Integrase Strand Transfer Inhibitor-based regimens. Requisition forms sent for HIV-1 genotypic resistance testing (GRT) between May 2015 and September 2019 were reviewed and participants experiencing virologic failure while on dolutegravir (DTG) or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Botswana

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Nucleic Acid

Share to Drug Resistance, Viral

Share to HIV Integrase Inhibitors

Share to Treatment Failure

Share to Viral Load

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 33807382
DOI: 10.3390/v13040594
PMCID: PMC8066386

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1 Subtype C Drug Resistance Mutations in Heavily Treated Patients Failing Integrase Strand Transfer Inhibitor-Based Regimens in Botswana.PMID 33807382Read ↗

High prevalence of reverse transcriptase inhibitors associated resistance mutations among people living with HIV on dolutegravir-based antiretroviral therapy in Francistown, Botswana.Semantic proximity Read ↗

Four-class drug-resistant HIV-1 subtype C in a treatment experienced individual on dolutegravir-based antiretroviral therapy in Botswana.Semantic proximity Read ↗

Impact of human immunodeficiency virus type 1 subtype C on drug resistance mutations in patients from Botswana failing a nelfinavir-containing regimen.Semantic proximity Read ↗

Prevalence of Rilpivirine and Etravirine Resistance Mutations in HIV-1 Subtype C-Infected Patients Failing Nevirapine or Efavirenz-Based Combination Antiretroviral Therapy in Botswana.Semantic proximity Read ↗

Low-frequency HIV-1 drug resistance mutations in antiretroviral naïve individuals in Botswana.Semantic proximity Read ↗

Limited emergence of resistance to integrase strand transfer inhibitors (INSTIs) in ART-experienced participants failing dolutegravir-based antiretroviral therapy: a cross-sectional analysis of a Northeast Nigerian cohort.Semantic proximity Read ↗

Limited emergence of resistance to Integrase strand transfer inhibitors (INSTIs) in HIV-experienced patients failing dolutegravir-based antiretroviral therapy: Cross-sectional analysis from a Northeast Nigerian cohortSemantic proximity Read ↗

Accumulation of drug resistance and loss of therapeutic options precede commonly used criteria for treatment failure in HIV-1 subtype-C-infected patients.Semantic proximity Read ↗

Characterization of HIV drug resistance mutations among patients failing first-line antiretroviral therapy from a tertiary referral center in Lusaka, Zambia.Semantic proximity Read ↗

HIV Drug Resistance Mutations in Non-B Subtypes After Prolonged Virological Failure on NNRTI-Based First-Line Regimens in Sub-Saharan Africa.Semantic proximity Read ↗

HIV-1 drug resistance mutations among individuals with low-level viraemia while taking combination ART in Botswana.Semantic proximity Read ↗

High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.