Article
High prevalence of reverse transcriptase inhibitors associated resistance mutations among people living with HIV on dolutegravir-based antiretroviral therapy in Francistown, Botswana.
The Journal of antimicrobial chemotherapy - 3 Mar 2025
Choga Ontlametse T, Lemogang Goitseone M, Choga Wonderful T, Muzanywa Gaonyadiwe, Shadreck Thembinkosi M, Ralegoreng Charity, Maruapula Dorcas, Moraka Natasha O, Koofhethile Catherine K, Mokgethi Patrick T, Seru Kedumetse, Zuze Boitumelo J L, Montshosi Patience, Gobe Irene, Motswaledi Modisa S, Musonda Rosemary, Mbulawa Mpaphi B, Makhema Joseph, Shapiro Roger, Lockman Shahin, Chebani Tony, Nawa Judith, Bochena Lindani, Moyo Sikhulile, Gaseitsiwe Simani
Abstract excerpt
OBJECTIVES: We assessed HIV-1 drug resistance profiles among people living with HIV (PLWH) with detectable viral load (VL) and on dolutegravir-based antiretroviral therapy (ART) in Botswana. METHODS: The study utilised available 100 residual HIV-1 VL samples from unique PLWH in Francistown who had viraemia at-least 6 months after initiating ART in Botswana's national ART program from November 2023 to January...
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