Article
Comparison of minimal inhibitory and mutant prevention drug concentrations of 4 fluoroquinolones against clinical isolates of methicillin-susceptible and -resistant Staphylococcus aureus.
International journal of antimicrobial agents - 1 Aug 2004
Metzler K, Hansen G M, Hedlin Peter, Harding Elizabeth, Drlica Karl, Blondeau J M
Abstract excerpt
Staphylococcus aureus remains an important human pathogen affecting both outpatients and those hospitalized. Increasing antimicrobial resistance is global but prevalence rates are variable for different geographical areas. Fluoroquinolones have been used to treat S. aureus infections and the newer quinolones have enhanced in vitro activity against this organism. The mutant prevention concentration (MPC) defines...
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