Article
Association between the TAP2 gene codon 665 polymorphism and Graves' disease.
Journal of clinical laboratory analysis - 1 Jan 2006
Chen Rong-Hsing, Wang Tze-Yuan, Chen Wen-Chi, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
A total of 95 patients with active Graves' disease (GD) and 105 normal healthy subjects were enrolled in this study, which attempted to determine whether single-site polymorphisms of the transporter associated with antigen processing 2 (TAP2) gene contribute to an individual's susceptibility to GD. Such polymorphisms were detected using polymerase chain reaction (PCR)-based restriction analysis. Associations...
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