Article
Association between the TAP1 gene codon 637 polymorphism and Graves' disease.
Endocrine - 1 Nov 2004
Chen Rong-Hsing, Chen Wen-Chi, Chen Ching-Chu, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
A total of 95 patients with Graves' disease (GD) and 105 normal healthy controls were enrolled in this study to determine how a single site polymorphism of the transporter associated with antigen processing 1 (TAP1) gene contributes to the pathogenesis of GD. The polymorphism was detected using polymerase chain reaction (PCR)-based restriction analysis. Associations between GD and the two-site polymorphisms of...
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