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Article

Isolation of chicken homolog of the <i>FOXL2</i> gene and comparison of its expression patterns with those of aromatase during ovarian development

29 Oct 2004

Abstract excerpt

Mutations in the forkhead transcription factor gene FOXL2 are involved in ovarian failure, which occurs in human BPES syndrome. This syndrome presents a sexually dimorphic expression, specific to the ovary in several vertebrates. We cloned the open reading frame of chicken FOXL2 (cFoxL2) and studied cFoxL2 expression in developing gonads and during adulthood to examine the role of FOXL2 in ovarian differentiation...

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PMID: 15517586
DOI: 10.1002/dvdy.20189

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