Article
Aromatase inhibition reduces expression of <i>FOXL2</i> in the embryonic chicken ovary
13 Apr 2005
Abstract excerpt
P450-aromatase is the terminal estrogen-synthesizing enzyme and a key gene in avian sex determination. Aromatase is expressed specifically in female gonads, but not male gonads, at the onset of sexual differentiation. This enzyme shows temporal and spatial colocalization with the forkhead transcription factor FOXL2 in the embryonic chicken ovary, suggesting a causal link. Mutations in FOXL2 are associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
