Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

WT1 and kidney progenitor cells

1 Apr 2010

Abstract excerpt

Kidney development has been studied over the past sixty years as a model of embryonic induction during organogenesis. Wilms' tumor-1 (WT1), that encodes a transcription factor and RNA-binding protein, was one of the first tumor suppressor genes identified, and was soon thereafter shown to be associated with syndromic forms of childhood kidney disease and gonadal dysgenesis. Kidney agenesis, resulting from a null...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Organ Donation and Transplantation
Share to Renal and related cancers
Share to Renal cell carcinoma treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20885852
DOI: 10.4161/org.6.2.11928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

WT1 and kidney progenitor cellsPMID 20885852Read ↗

The tumor suppressor WT1 drives progenitor cell progression and epithelialization to prevent Wilms tumorigenesis in human kidney organoidsSemantic proximity Read ↗

Wilms' tumor gene 1: lessons from the interface between kidney development and cancer.Semantic proximity Read ↗

Gene targeting in kidney development.Semantic proximity Read ↗

WT1 targetsGas1to maintain nephron progenitor cells by modulating FGF signalsSemantic proximity Read ↗

Exploring the Multifaceted Role of WT1 in Kidney Development and DiseaseSemantic proximity Read ↗

WT-1 is required for early kidney development.Semantic proximity Read ↗

Clinical Aspects of WT1 and the Kidney.Semantic proximity Read ↗

Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiationSemantic proximity Read ↗

Towards an understanding of kidney diseases associated with WT1 mutations.Semantic proximity Read ↗

Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice.Semantic proximity Read ↗

Wilms Tumorigenesis in Human Kidney OrganoidsSemantic proximity Read ↗

The molecular biology of Wilms' tumourSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.