Article
Construction of an additional metal-binding site in human metallothionein-2.
Journal of bioscience and bioengineering - 1 Apr 2006
Toyama Mitsutoshi, Sasaki Mariko, Hirayama Noriaki, Murooka Yoshikatsu, Yamashita Mitsuo
Abstract excerpt
We have constructed a new metal-binding site in the human metallothionein-2 (hMT-2), using the protein as a scaffold to investigate the structure and function of metal-binding. Potential metal-binding sites were designed within hMT-2 on the basis of structures generated by homology modeling. Amin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
