Double-strand break repair in bacteriophage T4: coordination of DNA ends and effects of mutations in recombinational genes.

doi:10.1016/j.dnarep.2006.03.007

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Article

Double-strand break repair in bacteriophage T4: coordination of DNA ends and effects of mutations in recombinational genes.

DNA repair - 13 Jul 2006

Shcherbakov Victor P, Plugina Lidiya, Shcherbakova Tamara, Sizova Svetlana, Kudryashova Elena

Abstract excerpt

Coordination of DNA ends during double-strand break (DSB) repair was studied in crosses of bacteriophage T4 in which DSBs were induced site-specifically by SegC endonuclease in the DNA of only one of the parents. Coupling of the genetic exchanges to the left and to the right of the DSB was measured in the wild-type genetic background as well as in T4 strains bearing mutations in several recombination genes: 47,...

Topics

Bacteriophage T4
Chromosome Breakage
DNA Repair
DNA, Viral
Genes, Viral
Models, Biological
Mutation
Recombination, Genetic

Source

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Identifiers

PMID: 16716767
DOI: 10.1016/j.dnarep.2006.03.007

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