Article
Double-strand break repair in bacteriophage T4: recombination effects of 3'-5' exonuclease mutations.
Genetics - 1 Dec 2006
Shcherbakov Victor P, Kudryashova E A, Shcherbakova T S, Sizova S T, Plugina L A
Abstract excerpt
The role of 3'-5' exonucleases in double-strand break (DSB)-promoted recombination was studied in crosses of bacteriophage T4, in which DSBs were induced site specifically within the rIIB gene by SegC endonuclease in the DNA of only one of the parents. Frequency of rII+ recombinants was measured in two-factor crosses of the type i x ets1, where ets1 designates an insertion in the rIIB gene carrying the cleavage...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
