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Article

Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Jun 2006

Nakamura Michihiko, Tanaka Nobuyuki, Kitamura Naomi, Komada Masayuki

Abstract excerpt

Endosomal sorting of ubiquitinated membrane proteins for trafficking to lysosomes is executed by a complex of two ubiquitin-binding proteins, Hrs and STAM, that localizes on a microdomain of early endosomes with a flat clathrin coat. AMSH is a deubiquitinating enzyme that interacts with STAM and is implicated in the down-regulation of epidermal growth factor receptor. AMSH has a close homolog, AMSH-like protein...

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Source

Identifiers

PMID: 16716190
DOI: 10.1111/j.1365-2443.2006.00963.x

Genes

STAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes.PMID 16716190Read ↗

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