Article
Genetic polymorphisms of chitotriosidase in Caucasian children with bronchial asthma.
International journal of immunogenetics - 1 Jun 2006
Bierbaum S, Superti-Furga A, Heinzmann A
Abstract excerpt
In humans, two types of chitinases have been identified: chitotriosidase I (CHIT1) and acid mammalian chitinase (AMCase). They are enzymes that cleave chitin, a polysaccharide contained in many different human parasites. So far, only little is known about their function in human and especially in human diseases. Recently we have described association of polymorphisms of AMCase with bronchial asthma in a pediatric...
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